Chicago White Sox · Pitcher
At 31, Seranthony Domínguez enters 2026 as a relief arm for the White Sox with mixed fantasy appeal and volatile performance trends. His early-season numbers show he's grabbed a prominent save role with 12 saves through limited appearances, though his ERA has climbed to 4.30 and his WHIP has ticked up to 1.33—concerning regression from his 2025 form when he posted a 3.16 ERA over more innings. Strikeout production remains serviceable with 35 K in 29.1 IP, but the elevated ERA and WHIP suggest he's facing command issues that fantasy managers should monitor closely. The save opportunities provide ceiling appeal in the category, yet health durability and recent performance trends make him a touchdown-dependent late-round closer play rather than a trustworthy cornerstone.
| Year | Team | G | GS | W | L | SV | ERA | WHIP | K | IP | BB |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018 | Philadelphia Phillies | 53 | 0 | 2 | 5 | 16 | 2.95 | 0.93 | 74 | 58.0 | 22 |
| 2019 | Philadelphia Phillies | 27 | 0 | 3 | 0 | 0 | 4.01 | 1.46 | 29 | 24.2 | 12 |
| 2021 | Philadelphia Phillies | 1 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 1 | 1.0 | 0 |
| 2022 | Philadelphia Phillies | 54 | 0 | 6 | 5 | 9 | 3.00 | 1.14 | 61 | 51.0 | 22 |
| 2023 | Philadelphia Phillies | 57 | 0 | 5 | 5 | 2 | 3.78 | 1.40 | 48 | 50.0 | 22 |
| 2024 | 2 teams▼ | 63 | 0 | 3 | 4 | 11 | 4.45 | 1.24 | 68 | 58.2 | 21 |
| 2025 | 2 teams▼ | 67 | 0 | 4 | 4 | 2 | 3.16 | 1.28 | 79 | 62.2 | 36 |
| 2026 | Chicago White Sox | 33 | 0 | 3 | 3 | 12 | 4.85 | 1.38 | 36 | 29.2 | 18 |
| Career | Totals | 355 | 0 | 26 | 26 | 52 | 3.62 | 1.23 | 396 | 335.2 | 153 |
Source: MLB Stats API · Multi-team seasons show combined totals — click to expand
| Year | Team | G | GS | W | L | SV | ERA | WHIP | K | IP | BB |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2012 | DSL Phillies | 15 | 11 | 4 | 4 | 0 | 3.48 | 1.32 | 40 | 67.1 | 26 |
| 2013 | DSL Phillies | 14 | 14 | 4 | 6 | 0 | 2.96 | 1.18 | 58 | 76.0 | 30 |
| 2014 | GCL Phillies | 14 | 0 | 2 | 2 | 0 | 3.12 | 1.54 | 24 | 26.0 | 14 |
| 2015 | GCL Phillies | 2 | 1 | 1 | 1 | 0 | 2.35 | 1.70 | 9 | 7.2 | 7 |
| 2016 | 2 teams▼ | 13 | 13 | 6 | 3 | 0 | 2.34 | 1.01 | 65 | 65.1 | 24 |
| 2017 | 2 teams▼ | 17 | 15 | 4 | 4 | 0 | 3.72 | 1.33 | 82 | 67.2 | 34 |
| 2018 | 2 teams▼ | 11 | 0 | 2 | 2 | 0 | 1.62 | 0.66 | 21 | 16.2 | 3 |
| 2021 | 3 teams▼ | 19 | 3 | 1 | 1 | 0 | 7.97 | 1.67 | 23 | 20.1 | 12 |
| 2022 | Lehigh Valley IronPigs | 1 | 0 | 0 | 0 | 0 | 0.00 | 2.00 | 1 | 1.0 | 2 |
| 2023 | Lehigh Valley IronPigs | 2 | 0 | 0 | 0 | 0 | 0.00 | 1.00 | 5 | 2.0 | 1 |
| Career | Totals | 108 | 57 | 24 | 23 | 0 | 3.29 | 1.25 | 328 | 349.3 | 153 |
Source: MLB Stats API · Multi-team seasons show combined totals — click to expand